Funding Opportunities

NIHR (National Institute for Health Research)

NIHR

The following funding opportunities are currently available through the National Institute for Health Research.

 

NIHR: 18/33 – Valuing the benefits and harms of antenatal and new born screening programmes in the UK
Which benefits and harms should be incorporated in the health economic assessment of antenatal and newborn screening programmes in the UK? How may these benefits and harms best be measured and valued?
1. Interventions: UK antenatal and newborn screening programmes.
2. Setting: UK.
3. Study design: A mixed methods scoping study to identify the range of methods, utilities and disutilities used in the health economic assessment of antenatal and newborn screening in the UK and similar developed health systems. It should include a systematic review that incorporates existing models and grey literature, supplemented by a narrative review that explores the strengths and weaknesses of the different approaches used for measurement and valuation. Further qualitative work should be carried out with parents/ carers, professionals and national stakeholders to consider how the wider impacts of screening should be incorporated into the UK assessment of antenatal and newborn screening programmes, as well as those issues that affect babies and children themselves.
4. Important outputs: Description of currently available health related quality of life utility measures and instruments; description of the scope of benefits and harms; discussion of the strengths and weaknesses of current approaches and instruments for valuation. Other outputs: Identified gaps in the evidence; an outline of the research designs that would (i) extend current methods to better inform UK antenatal and newborn screening or, if required, (ii) to develop new more suitable instruments for use in the UK.
Deadline: 1 August 2018, 1.00pm
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NIHR: 18/32 Management of Orthostatic Hypotension
What is the effectiveness and cost-effectiveness of fludrocortisone and midodrine for the management of orthostatic hypotension?
1. Interventions: (i) Fludrocortisone plus usual care; (ii) midodrine plus usual care (applicants to define the dosage regimens).
2. Patient group: Adults with orthostatic hypotension refractory to education, lifestyle and medication modifications (applicants to define and justify).
3. Setting: Secondary care.
4. Control: Usual care (applicants to define and justify).
5. Study design: Three arm randomised controlled trial to compare fludrocortisone, midodrine and usual care; with internal pilot to test willingness and ability to recruit and randomise. Applicants may wish to consider an adaptive study design.
6. Important outcomes: Falls (number and time to event); quality of life; activities of daily living; syncope. Other outcomes: Hospitalisation, acceptability, cost-effectiveness, adverse effects. 7. Minimum duration of follow-up: 6 months. Longer-term follow up: Applicants to consider building in provision, if appropriate, for a simple mechanism for long-term follow up using routine data bases/sets; including obtaining consent for this from participants at trial entry.
Deadline: 1 August 2018, 1.00pm
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NIHR: Research and Innovation for Global Health Transformation Call 1
Applications are invited for Call 1 of the new NIHR Research and Innovation for Global Health Transformation (RIGHT) programme. Delivering challenge-led research that will primarily benefit the health and wealth of the poorest individuals living in low and middle income countries (LMICs), the RIGHT programme forms part of the nation’s commitment to Official Development Assistance (ODA) and complements recent investment in NIHR Global Health Research Groups and Units.
RIGHT is a two stage competition, subject to independent peer review and international panel assessment at both stages. The total amount of NIHR funding available for this competition is up to £30 million. Awards will typically range between £3m-5m over 3-4 years for ODA-eligible research to start in June 2019.
In Call 1, the programme seeks to fund high quality research ideas in three areas of unmet need and underinvestment in LMICs – epilepsy, infection-related cancer and severe stigmatising skin diseases.
Deadline: 1 August 2018, 1.00pm
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NIHR: 18/30 – Hysteroscopic removal of retained placenta
For women presenting with secondary postpartum haemorrhage, is it feasible to conduct a study comparing hysteroscopic removal of retained placenta with usual care?
1. Intervention: Operative hysteroscopy for removal of retained placenta.
2. Patient group: Post-partum women presenting with secondary postpartum haemorrhage (PPH) undergoing surgical management of retained placenta. Consideration should be given to the length of time taken for women to present for surgical management. To be defined as part of this feasibility study.
3. Setting: To be determined by this research.
4. Comparator: Current best practice – to be defined as part of this feasibility study.
5. Study design: A stand-alone feasibility study, including a survey of current practice and qualitative work with women, to determine whether a trial is possible and to establish key elements of the potential future trial design.
6. Important outcomes and outputs: Current practice with regards to management of secondary PPH; determination of equipoise; definition of patient group eligibility criteria; numbers of women potentially eligible for recruitment; acceptability of randomisation to clinicians and women; determination of important outcomes of a potential full trial; feasibility of trial delivery. A randomised element is not expected as part of this commission. A decision whether to advertise for a full trial will be made at a later date once results of the feasibility report are known.
Deadline: 1 August 2018, 1.00pm
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NIHR: 18/59 – Mechanisms of Action of Health Interventions
The EME Programme invites proposals for hypothesis driven research into the underlying mechanisms of action of clinical and public health interventions. Studies must utilise patients or samples from identifiable cohorts from current or completed NIHR-funded projects from the following programmes: i4i, EME (including the MRC/NIHR transferred portfolio), HS&DR, HTA, PHR, RfPB and PGfAR.
Proposals will be accepted across a wide range of interventions; including behavioural, pharmaceutical, psychological, surgical and public health interventions. The research should be hypothesis driven, relevant to the intervention and outcomes proposed by the original study and add significantly to the scientific understanding of the mechanisms of action of the intervention.
Deadline:  21 August 2018, 1.00pm
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NIHR: 18/62 Efficacy and Mechanism Evaluation: Mental Health Themed Call
A call for research for the promotion of good mental health and the prevention or treatment of mental ill health 1 across the whole life course.
The National Institute for Health Research (NIHR) welcomes proposals for clinical and applied health research that evaluate healthcare interventions, health services, social care or public
health measures operating at either the individual, or the population level. Issues of particular interest include proposals that utilise new digital health technologies or investigate their effects.
Deadline: 21 August 2018
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NIHR: EME Programme – Functional Imaging Research Funding

The EME Programme is considering this topic for future commissioned research and the potential advert date for this is 22 August 2018.

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NIHR Senior Investigators
NIHR Senior Investigators are fundamental to the NIHR Faculty and include some of the country’s foremost researchers, making an outstanding contribution to clinical and applied health and social care research.
Leading researchers funded by the NIHR (including the Policy Research Programme); and who are employed by an NHS Trust, university or charity based in England, are encouraged to apply. NIHR Research Professors reaching the end of their term are also invited to apply; providing their term ends by 01 April 2018.
Applications are invited from all relevant fields. For this round, we would encourage applications in the important fields of geriatric medicine and old age psychiatry.
Deadline: 28 August 2018, 1.00pm
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NIHR: 18/67 HTA Mental Health Themed Call (evidence synthesis)
The NIHR welcomes proposals for clinical and applied health research that evaluate healthcare interventions, health services, social care or public health measures operating at either the individual, or the population level. Issues of particular interest include proposals that utilise new digital health technologies or investigate their effects.
Studies may include individuals with co-morbid conditions included in HRCS category ‘Neurological’ provided the main focus remains the mental health condition.
Applications are encouraged that include geographic populations with high disease burden which have been historically under served by NIHR research activity.
Deadline: 29 August 2018
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NIHR: Senior Investigator Fellowship 12th Annual Competition

NIHR Senior Investigators are fundamental to the NIHR and include some of the country’s foremost researchers, making an outstanding contribution to clinical and applied health and social care research.

Leading researchers funded by the NIHR and who are employed by an NHS Organisation, University or charity based in England, are encouraged to apply. NIHR Research Professors reaching the end of their term are also invited to apply; providing their term ends by 01 April 2019 and they have ‘Active’ NIHR funding at the time of application.

Deadline: 29 August 2018, 1.00pm.  This scheme will re-open in June 2019. 

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NIHR: Research Professorships

These awards aim to fund future research leaders to promote effective translation of research (‘bench to bedside [T1] and ‘campus to clinic’ [T2]) and strengthen research leadership at the highest academic levels.

Dates: Round 8 has now closed for applications.  Round 9 is currently expected to open mid/late September 2018, however this is subject to change.

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NIHR: i4i Connect Call 2

i4i Connect is aimed at small to medium-sized enterprises (SMEs) in need of a funding boost to reach the next stage in the development pathway. Offering between £50,000-£150,000 over a 6-12 month period, its primary aim is to help SMEs get to a point where they can apply for further funding, in particular for a full i4i Product Development Award (PDA), or to support projects at any stage of the translational research and development pathway to further de-risk them for follow on investment. This will enable accelerated development of promising medical technologies, in line with recommendations from the Government’s Accelerated Access Review.

Deadline: EOI 11 September 2018, 1.00pm. Full business plan if invited 23 October 2018, 1.00pm

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NIHR: HTA 18/43 – Rotation of the fetal head at full cervical dilatation

The Health Technology Assessment Programme is accepting stage 1 applications to their commissioned workstream for this primary research topic.

Deadline: 19 September 2018, 1.00pm

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18/90 Integrated Mental Health and Physical Health and Care Services for health economies

18/91 Rural health and care workforce

18/92 Evaluating approaches to health and care services commissioning and provision with the third sector in the UK

Deadline: 13 September 2018, 1.00pm

18/37 – Repair of digital nerve injury

18/39 – Earlier active management of ovarian hyperstimulation syndrome

18/40 – Short-term use of benzodiazepines for the acute management of acute low back pain

18/41 – Clinical and cost effectiveness of alternative urinary catheter design

18/43 – Rotation of the fetal head at full cervical dilatation

18/44 – Pre-hospital pain management

18/52 – Management of isolated or incidental subsegmental pulmonary embolism

Deadline: 19 September 2018, 1.00pm

18/47 – Outpatient cervical ripening for induction of labour

18/45 – Proton pump inhibitor therapy for refractory gastro-oesophageal reflux symptoms

18/42 – Cystic fibrosis

18/50 – Frail older people in primary care

18/49 – Radiofrequency denervation for low back pain

18/48 – Radiotherapy in first-line treatment of diffuse large B-cell lymphoma

18/51 – Extended duration haemodialysis

18/46 – Pharmacological management of post-traumatic seizures

Deadline: 26 September 2018, 1.00pm

 

NIHR 18/70: Fire and Rescue Visits to Improve Health Outcomes
The NIHR Public Health Research Programme wishes to commission research on the effectiveness and cost-effectiveness of interventions that have been or have the potential to be delivered in the UK by Fire and Rescue Services to improve health outcomes and reduce health inequalities.
Deadline: 6 November 2018, 1.00pm
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NIHR: Research for Patient Benefit Programme – Competition 37Applications are invited for research proposals that are concerned with the day-to-day practice of health service staff, and which have the potential to have an impact on the health or wellbeing of patients and users of the NHS. As a response mode researcher-led programme, RfPB does not specify topics for research, but encourages proposals for projects which address a wide range of health service issues and challenges.Deadline: 21 November 2018, 1.00pmClick here for more information. 

NIHR: i4i Product Development Awards Call 17 These awards support any stage of the translational research and development pathway, including the clinical development of laboratory-validated technologies or interventions.Highlight Notices:

‘Complex Health and Care Needs in Older People’. Relevant research areas include frailty, transitions in care, service delivery and models of care, medicines management/polypharmacy, promoting healthy ageing/preventing ill health and patient-centred decision making.

‘Brain Tumours’. This highlight notice indicates the continuing interest of NIHR in receiving research proposals in this area, and it encourages collaborative applications that demonstrate how they build on recent initiatives and investment in the area made by the NIHR, the MRC and other research funders

Themed Calls:

‘Promotion of good mental health and the prevention or treatment of mental ill health’. Proposals are invited for clinical and applied health research that evaluate healthcare interventions, health services, social care or public health measures operating at either the individual, or the population level. Issues of particular interest include proposals that utilise new digital health technologies or investigate their effects.

Deadline: call opens 31 October 2018 and closes 12 December 2018, 1.00pm.  Call 18 will launch on 24 April 2019.

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Public Health Research Programme Rapid Funding Scheme
The Rapid Funding Scheme (RFS) offers researchers the opportunity to apply for funds to conduct rapid baseline data collection, as well as other feasibility work, prior to intervention implementation, for time-limited opportunities such as a natural experiment or similar evaluations of a new public health intervention.
The RFS has been set up to provide the public health research community with an accelerated route to funding for small-scale, short and time sensitive proposals that demonstrate a need for a rapid commissioning process to be followed. Funding will be offered, subject to appropriate scientific scrutiny, on the understanding that a full application to support completion of the evaluation will be forthcoming at an appropriate time point.
Proposals submitted to the RFS will be for:
•a value of £50,000 or less
•a duration of six months or less
•for based line data collection/ other feasibility work
•taking advantage of a time limited natural experiment opportunity
•aiming towards the submission of a full evaluation
If you would like your proposal to be considered for the RFS, please contact phr@nihr.ac.uk with a summary of your intended project of no more than one page of A4 in length describing both the proposed work and the reasons for the urgency, in particular, why this proposal could not be considered through the standard commissioning timelines such as the researcher-led work stream.
Deadline: 31 December 2018
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HEE/NIHR Integrated Clinical Academic Programme for non-medical healthcare professions

The HEE and NIHR Integrated Clinical Academic (ICA) Programme provides personal research training awards for healthcare professionals (excluding doctors and dentists) who wish to develop careers that combine clinical research and research leadership with continued clinical practice and clinical development. Applicants must belong to one of the eligible professions.

Five levels of award are available, each requiring the support of clinical and academic host organisations, which together form a career pathway for aspiring and developing non-medical clinical academics:

Internships – competition opens in February 2019

Pre-doctoral Clinical Academic Fellowship – competition opens February 2019

Clinical Doctoral Research Fellowship – competition opens March 2019

Clinical Lectureship – competition opens March 2019

Senior Clinical Lectureship – competition opens March 2019

Doctoral and Post-Doctoral award holders are also eligible for ICA Programme-funded mentorship support through the ICA Mentorship and Outreach Programme.

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